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Allegro Ophthalmics announced the expansion of the company’s anti-integrin portfolio with the new topical dry eye disease drug candidate ALG-1007. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate), currently being developed for diabetic macular edema (DME) and intermediate dry age-related “ALG-1007 represents Allegro’s first exploratory drug beyond the retina. We recognize the need to bring in independent external expertise that complements our company’s strengths and are ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate),currently being developed for diabetic macular edema (DME) and intermediate Allegro Ophthalmics, LLC has announced earlier this week the company’s expansion of its anti-integrin portfolio with the new front-of-the-eye-drug candidate ALG-1007. ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States. Allegro has expanded its anti-integrin portfolio with the development of ALG-1007 for topical use in dry eye disease Its lead investigational compound , risuteganib , is being studied in dry AMD and DME Allegro has a clear path forward and is gearing up for a larger US Phase 2b/3 trial in dry AMD in 1H 2020 ALG-1007 for topical use in dry eye disease demonstrated an improvement in both signs and symptoms of DED Allegro has initiated a second larger exploratory ex-US DED study looking at higher doses in a vehicle-controlled study

proof-of-concept clinical trial of the new investigational ALG-1007 topical drop drug candidate in patients with dry eye disease (DED). Allegro’s other ophthalmology assets include ALG-1007, a topical integrin regulator candidate for the treatment of dry eye disease. The candidate is in Phase II development outside the US. The terms of the deal include an option payment of $50m completed in two instalments, ALG-1007, a topical drop, is the company’s second exploratory integrin-regulating drug candidate. In May, Allegro announced that the ex-U.S.

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Thalatta, 55 S54, SK55 AD8531ARTZ MAX2338EGI LT1007CS8 LTc1326CS8-2.5 LT1622CMS8 AD AD AD ADAPTEC Agilent ALCATEL ALCATEL ALLEGRO ALTERA AMCC AMD C915AF C915AF C1007AF C1197AF C1221AF C1220AF C1220AF CCT186 CCT38 CCT38 Allegro 1.0 Allegro 1.1 Allegro 1.3 Allegro 1.5 Allegro 1.7 949-427-1007. Elliptograph Personeriasm · 949-427- Alger Stohr. 949-427-6212.

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NOV-07 (Novaliq) BL-1230 (Bioline Rx) Palovarotene (Clementia/Ipsen) SI-614 (Seikagaku) 2019-05-14 2020-09-21 Allegro has also expanded the company’s integrin-regulating portfolio with the front-of-the-eye drug candidate ALG-1007. ALG-1007 is a topical therapeutic compound in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people around the world. ALG-1007 is a topical integrin regulator in development for potential use in patients with dry eye disease. ALG-1007 demonstrated a strong signal in an ex-U.S.

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The views and opinions expressed herein are the views ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate ®), currently being developed for diabetic macular edema (DME) and intermediate dry age-related macular degeneration (intermediate dry AMD).
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ALG 1007, a peptide integrin inhibitor is being developed by Allegro Ophthalmics for the treatment of dry eye disease (DED). ALG 1007 inhibits the leucocyte ALG 1007 - AdisInsight ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate ® ), currently being developed for diabetic macular edema (DME) and intermediate Expanding its integrin-regulating portfolio, Allegro has developed ALG-1007 for topical use in dry eye disease. ALG-1007 demonstrated promising results in an ex-U.S. proof-of-concept study in humans, and is currently being evaluated in a second and larger ex-U.S. Phase 2 study. ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States.

proof-of-concept clinical trial in which it showed a dose response curve and that it was generally well-tolerated. Expanding its anti-integrin portfolio, Allegro has developed ALG-1007, an anti-integrin drug candidate for topical use in DED. ALG-1007 has successfully completed an ex-U.S. proof-of-concept study in humans, and is currently being evaluated in a larger ex-U.S.